Invention Grant
- Patent Title: Methods for expressing proteins in axons
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Application No.: US12832698Application Date: 2010-07-08
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Publication No.: US10941186B2Publication Date: 2021-03-09
- Inventor: Samie R. Jaffrey , Ulrich Hengst
- Applicant: Samie R. Jaffrey , Ulrich Hengst
- Applicant Address: US NY New York; US NY New York
- Assignee: Samie R. Jaffrey,Ulrich Hengst
- Current Assignee: Samie R. Jaffrey,Ulrich Hengst
- Current Assignee Address: US NY New York; US NY New York
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07K14/47 ; C12N15/113 ; C12N15/86
Abstract:
The invention relates to expressing proteins in the axons of mammalian neurons. The invention provides nucleic acids that can be used to express a selected polypeptide in neuronal axons, viruses that can be used deliver nucleic acids of the invention into neuronal axons, as well as methods for doing so. Thus, the invention provides pharmaceutical compositions comprising viruses of the invention, as well as their use in methods of treating injured axons or conditions associated with aberrant axon growth or function.
Public/Granted literature
- US20100330038A1 METHODS FOR EXPRESSING PROTEINS IN AXONS Public/Granted day:2010-12-30
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