Invention Grant
- Patent Title: Carbohydrate content of CTLA4 molecules
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Application No.: US16042977Application Date: 2018-07-23
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Publication No.: US10941189B2Publication Date: 2021-03-09
- Inventor: Kirk J. Leister , Eugene J. Schaefer , Ronald Charles Bates , Elizabeth A. Bramhall , David Michael Didio , Robert Donaldson , Alan R. Flesher , Helen Gray Haggerty , David Henry Kirkley , John Malcolm Tabor , Lee K. Tay , Pallaiah Thammana , Ajoy Velayudhan , David Edward Smolin , Reb J. Russell , Thomas James Vanden Boom , Dean Woodrow Brownell , Jeffrey Schrimsher , Joyce Patricia Whitehead
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K14/705 ; A61K38/19 ; C07K16/28 ; A61K38/00 ; B01D15/38
Abstract:
The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof. The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.
Public/Granted literature
- US20190062399A1 CARBOHYDRATE CONTENT OF CTLA4 MOLECULES Public/Granted day:2019-02-28
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