Invention Grant
- Patent Title: Method of manufacturing dual-specific T-cells for use in cancer immunotherapy
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Application No.: US15777399Application Date: 2016-11-18
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Publication No.: US10941381B2Publication Date: 2021-03-09
- Inventor: Weiguo Cui
- Applicant: Versiti Blood Research Institute Foundation, Inc.
- Applicant Address: US WI Milwaukee
- Assignee: Versiti Blood Research Institute Foundation, Inc.
- Current Assignee: Versiti Blood Research Institute Foundation, Inc.
- Current Assignee Address: US WI Milwaukee
- Agency: Quarles & Brady LLP
- International Application: PCT/US2016/062831 WO 20161118
- International Announcement: WO2017/112184 WO 20170629
- Main IPC: C12N5/0783
- IPC: C12N5/0783 ; A61K35/17 ; A61K9/00 ; A61K35/00 ; A61K39/00 ; A61P35/00
Abstract:
The present invention relates to autologous dual-specific lymphocytes, methods of making and uses for the treatment of tumors. In particular, the invention relates to methods producing autologous dual-specific lymphocytes comprising an endogenous receptor for at least one tumor associated antigen and an exogenous receptor for a strong antigen.
Public/Granted literature
- US20180334651A1 METHOD OF MANUFACTURING DUAL-SPECIFIC T-CELLS FOR USE IN CANCER IMMUNOTHERAPY Public/Granted day:2018-11-22
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