Invention Grant
- Patent Title: Methods and kits for highly multiplex single primer extension
-
Application No.: US15767312Application Date: 2016-10-14
-
Publication No.: US10941438B2Publication Date: 2021-03-09
- Inventor: Yexun Wang , Quan Peng
- Applicant: QIAGEN SCIENCES, LLC
- Applicant Address: US MD Germantown
- Assignee: QIAGEN SCIENCES, LLC
- Current Assignee: QIAGEN SCIENCES, LLC
- Current Assignee Address: US MD Germantown
- Agency: Seed IP Law Group LLP
- International Application: PCT/US2016/057073 WO 20161014
- International Announcement: WO2017/066592 WO 20170420
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12N9/12 ; C12Q1/6848 ; C12Q1/6844 ; C12Q1/6869 ; C12Q1/686
Abstract:
The present disclosure provides methods and kits for highly multiplex single primer extensions using a MutS protein and Mg2+ at a concentration higher than that in a typical PCR reaction. Also disclosed is the use of such methods and kits in next generation sequencing.
Public/Granted literature
- US20190062822A1 METHODS AND KITS FOR HIGHLY MULTIPLEX SINGLE PRIMER EXTENSION Public/Granted day:2019-02-28
Information query
