Invention Grant
- Patent Title: Urothelial cancer and methods of detection and targeted therapy
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Application No.: US15073337Application Date: 2016-03-17
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Publication No.: US10941450B2Publication Date: 2021-03-09
- Inventor: Masamichi Hayashi , Elisa Guida , Mohammad Hoque
- Applicant: THE JOHNS HOPKINS UNIVERSITY
- Applicant Address: US MD Baltimore
- Assignee: THE JOHNS HOPKINS UNIVERSITY
- Current Assignee: THE JOHNS HOPKINS UNIVERSITY
- Current Assignee Address: US MD Baltimore
- Agency: Johns Hopkins Technology Ventures
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6886 ; A61K31/711 ; A61K31/7068
Abstract:
The invention provides methods for detecting a cellular proliferative disorder (e.g., urothelial cancer) in a subject by assessing the methylation status of the GULP1 promoter in a nucleic acid sample. The methods of the invention are useful for diagnostic, prognostic as well as therapeutic regimen predictions.
Public/Granted literature
- US20160273051A1 UROTHELIAL CANCER AND METHODS OF DETECTION AND TARGETED THERAPY Public/Granted day:2016-09-22
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