Invention Grant
- Patent Title: Methods and systems of detecting plasma protein biomarkers for diagnosing acute exacerbation of COPD
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Application No.: US15575307Application Date: 2016-05-17
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Publication No.: US10942188B2Publication Date: 2021-03-09
- Inventor: Don D. Sin , Raymond T. Ng , Bruce McManus , Zsuzsanna Hollander , Virginia Chen
- Applicant: THE UNIVERSITY OF BRITISH COLUMBIA
- Applicant Address: CA Vancouver
- Assignee: THE UNIVERSITY OF BRITISH COLUMBIA
- Current Assignee: THE UNIVERSITY OF BRITISH COLUMBIA
- Current Assignee Address: CA Vancouver
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/IB2016/052872 WO 20160517
- International Announcement: WO2016/185385 WO 20161124
- Main IPC: G01N33/68
- IPC: G01N33/68
Abstract:
Described are compositions and methods for diagnosing acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Multiple reaction monitoring mass spectrometry (MRM-MS) was used to quantify the amount of protein biomarkers in plasma samples from human subjects. The amount of the biomarkers in the sample can distinguish AECOPD from a stable or convalescent state of COPD, or from a subject without COPD.
Public/Granted literature
- US20190383830A1 METHODS AND SYSTEMS OF DETECTING PLASMA PROTEIN BIOMARKERS FOR DIAGNOSING ACUTE EXACERBATION OF COPD Public/Granted day:2019-12-19
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