In some aspects, a method for mediation of a screenshot capture by a client application based on policy includes identifying, by a client application on a client device, a policy for mediating one or more screenshots of content displayed via the client application. An embedded browser within the client application accesses a network application of one or more servers. The method further includes intercepting, by the client application, a request to capture a screenshot of at least a portion of the network application being displayed, determining, by the client application, one or more mediation actions to perform on the screenshot responsive to the policy, performing, by the client application, the one or more mediation actions on the screenshot, and providing, by the client responsive to the request, the screenshot resulting from the one or more mediation actions.