Devices, systems, and methods of intravascular procedure training are provided. In some instances, the method includes outputting, from a computing device to a display device in communication with the computing device, a first visual representation of a blood vessel; determining, using the computing device, a first course of action based on the first visual representation of the blood vessel; receiving, at an input device in communication with the computing device, a user input associated with a second course of action; comparing, using the computing device, the first and second courses of action; and outputting, from the computing device to the display, a comparison of the first and second courses of action. Associated devices and systems are also provided.