Invention Grant
- Patent Title: 68Ge/68Ga generator
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Application No.: US16073973Application Date: 2017-12-27
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Publication No.: US10943709B2Publication Date: 2021-03-09
- Inventor: Jussi Jernström , Konstantin Zhernosekov , Yury Totskiy , Mark Harfensteller , Marian Meckel
- Applicant: ITM Isotopen Technologien München AG
- Applicant Address: DE Garching
- Assignee: ITM Isotopen Technologien München AG
- Current Assignee: ITM Isotopen Technologien München AG
- Current Assignee Address: DE Garching
- Agency: Lewis Kohn & Walker LLP
- Agent Kari Moyer-Henry
- Priority: EP16206969 20161227
- International Application: PCT/EP2017/084627 WO 20171227
- International Announcement: WO2018/122250 WO 20180705
- Main IPC: G21G4/08
- IPC: G21G4/08 ; C01G31/02 ; C01G33/00 ; C01G35/00 ; G21G1/00 ; G21G1/10 ; G21G4/10 ; A61K51/00

Abstract:
A 68Ge/68Ga generator for a continuous production of a 68Ga daughter nuclide, wherein the 68Ge parent nuclide thereof is specifically adsorbed to an inorganic support material and wherein said 68Ge parent nuclide continuously decays to 68Ga by electron capture at a half-life of 270.82 d, wherein the inorganic support material is at least one oxide of a metal being selected from the group consisting of: Vanadium, Niobium and Tantalum. The use of at least one oxide of a metal being selected from the group consisting of: Vanadium, Niobium and Tantalum as an inorganic support material for the manufacture of a 68Ge/68Ga generator for pharmaceutical purposes. With the inorganic support material of the present invention, it is possible to load 68Ge/68Ga generators with up to 8000 MBq of 68Ge (corresponding to 80 μg Germanium).
Public/Granted literature
- US20190066860A1 68Ge/68Ga Generator Public/Granted day:2019-02-28
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