Methods and apparatus are disclosed for security event detection through virtual machine introspection. Example methods involve monitoring usage of a plurality of resources by a first virtual machine executing on a computing device by a monitoring agent, the monitoring agent executing on the computing device separate from the first virtual machine. Example methods further involve detecting a potential security event by comparing the usage of the plurality of resources to resource usage patterns. Example methods further involve assigning a severity level to the detected potential security event, and initiating a security action defined for the assigned severity level.