Invention Grant
- Patent Title: Heteroaryl compounds and their use as therapeutic drugs
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Application No.: US16141044Application Date: 2018-09-25
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Publication No.: US10947215B2Publication Date: 2021-03-16
- Inventor: Myeong-Seop Kim , Sumin Kim , Jin Kwan Kim , Hadong Kim , Ki Moon Ryu , Seong Jin Park , Taesun Park , Joon-Ho Sheen , Taeyoung Yoon , Mi Yeon Jang
- Applicant: Dong-A Socio Holdings Co., Ltd.
- Applicant Address: KR Seoul
- Assignee: Dong-A Socio Holdings Co., Ltd.
- Current Assignee: Dong-A Socio Holdings Co., Ltd.
- Current Assignee Address: KR Seoul
- Main IPC: C07D213/82
- IPC: C07D213/82 ; C07D401/04 ; C07D401/10 ; C07D401/12 ; C07D403/04 ; C07D401/14 ; C07D405/14 ; C07D409/14 ; C07D417/04 ; C07D417/14
Abstract:
The present invention provides heterocyclic compounds, the stereoisomer thereof, the enantiomer thereof, or the pharmaceutically acceptable salt, which are capable of modulating the activity of Mer receptor tyrosine kinase (MERTK). This invention also provides pharmaceutical compositions thereof, methods to prepare the said compounds, and the use of such compounds as a medicament.
The present invention is directed to MERTK inhibitory compounds with marked potency, thereby having an outstanding potential for a pharmaceutical intervention of cancer and any other diseases related to MERTK dysregulation.
The present invention is directed to MERTK inhibitory compounds with marked potency, thereby having an outstanding potential for a pharmaceutical intervention of cancer and any other diseases related to MERTK dysregulation.
Public/Granted literature
- US20190119252A1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS Public/Granted day:2019-04-25
Information query
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