Invention Grant
- Patent Title: Forms of a PI3K delta selective inhibitor for use in pharmaceutical formulations
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Application No.: US16557091Application Date: 2019-08-30
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Publication No.: US10947244B2Publication Date: 2021-03-16
- Inventor: Swaroop K. Vakkalanka
- Applicant: Rhizen Pharmaceuticals SA
- Applicant Address: CH La Chaux-de-Fonds
- Assignee: Rhizen Pharmaceuticals SA
- Current Assignee: Rhizen Pharmaceuticals SA
- Current Assignee Address: CH La Chaux-de-Fonds
- Agency: Blank Rome LLP
- Priority: IN2596/CHE/2014 20140527,IN2597/CHE/2014 20140527
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D487/04 ; A61P29/00 ; A61P35/00 ; A61K45/06 ; C07C309/30
Abstract:
The present invention relates to solid state forms of a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta inhibitor (S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one (TGR-1202). The present invention also relates to methods of preparing the same, pharmaceutical compositions containing them, and methods of treating a PI3K kinase mediated disease or disorder, such as cancer, by administering the same.
Public/Granted literature
- US20190382411A1 FORMS OF A PI3K DELTA SELECTIVE INHIBITOR FOR USE IN PHARMACEUTICAL FORMULATIONS Public/Granted day:2019-12-19
Information query
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