Invention Grant
- Patent Title: Peptides of use in the preventive and curative treatment of alopecia
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Application No.: US15766860Application Date: 2016-10-10
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Publication No.: US10947273B2Publication Date: 2021-03-16
- Inventor: Michel Hocquaux , Stéphanie Almeida Épouse Scalvino , Elian Lati , Joanna Bakala
- Applicant: Institut Europeen de Biologie Cellulaire , Centre de Recherches Biologiques et d'Experimentations Cutanees , Centre National de la Recherche Scientifique (CNRS)
- Applicant Address: FR Ramonville St. Agne; FR Longjumeau; FR Paris
- Assignee: Institut Europeen de Biologie Cellulaire,Centre de Recherches Biologiques et d'Experimentations Cutanees,Centre National de la Recherche Scientifique (CNRS)
- Current Assignee: Institut Europeen de Biologie Cellulaire,Centre de Recherches Biologiques et d'Experimentations Cutanees,Centre National de la Recherche Scientifique (CNRS)
- Current Assignee Address: FR Ramonville St. Agne; FR Longjumeau; FR Paris
- Priority: FR1559655 20151009
- International Application: PCT/EP2016/074238 WO 20161010
- International Announcement: WO2017/060533 WO 20170413
- Main IPC: C07K7/06
- IPC: C07K7/06 ; C07K5/11 ; C07K5/09 ; A61K8/64 ; A61Q7/00 ; A61K38/00 ; A61K38/06 ; A61K38/07 ; A61K38/08

Abstract:
The object of the present invention relates to a novel family of peptide conjugates of formula (I): A-X1-X2-Pro-Ala-X—B (I) wherein: A represents a hydrogen atom, a C6 to C20 acyl group or a cholesterol residue; X1 represents a covalent bond, an alanine or a proline; X2 represents an arginine, a lysine, or an alanine; X represents a lysine, an alanine, or a phenylalanine; and B represents a hydroxyl or an amine; or one of its preferentially pharmaceutically, dermatologically or cosmetically acceptable salts, as well as their synthesis processes and their uses for reducing hair loss and stimulating hair growth.
Public/Granted literature
- US20180291061A1 PEPTIDES OF USE IN THE PREVENTIVE AND CURATIVE TREATMENT OF ALOPECIA Public/Granted day:2018-10-11
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