Invention Grant
- Patent Title: Interferon production using short RNA duplexes
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Application No.: US14776463Application Date: 2014-03-13
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Publication No.: US10947543B2Publication Date: 2021-03-16
- Inventor: Anna Marie Pyle , Andrew Kohlway , Dahai Luo , David Rawling , Akiko Iwasaki
- Applicant: Yale University
- Applicant Address: US CT New Haven
- Assignee: Yale University
- Current Assignee: Yale University
- Current Assignee Address: US CT New Haven
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle; Domingos J. Silva
- International Application: PCT/US2014/025578 WO 20140313
- International Announcement: WO2014/159990 WO 20141002
- Main IPC: C12N15/115
- IPC: C12N15/115 ; A61K38/21 ; A61K31/713 ; A61K45/06
Abstract:
The present invention provides a small hairpin nucleic acid molecule that is capable of stimulating interferon production. The nucleic acid molecule of the present invention has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises a 5′ triphosphate or a 5′ diphosphate.
Public/Granted literature
- US20160046943A1 Interferon Production Using Short RNA Duplexes Public/Granted day:2016-02-18
Information query
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