Invention Grant
- Patent Title: Methods for detecting BRAF in cancer
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Application No.: US15523179Application Date: 2015-10-29
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Publication No.: US10947597B2Publication Date: 2021-03-16
- Inventor: David J. Panka
- Applicant: BETH ISRAEL DEACONESS MEDICAL CENTER, INC
- Applicant Address: US MA Boston
- Assignee: BETH ISRAEL DEACONESS MEDICAL CENTER, INC
- Current Assignee: BETH ISRAEL DEACONESS MEDICAL CENTER, INC
- Current Assignee Address: US MA Boston
- Agency: Greenberg Traurig, LLP
- Agent Melissa Hunter-Ensor; Jana E. Harris
- International Application: PCT/US2015/058119 WO 20151029
- International Announcement: WO2016/069928 WO 20160506
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6886 ; A61K31/437 ; A61K31/506 ; A61K31/519

Abstract:
The invention features compositions and methods for detecting and quantifying BRAFV600E in a sample of a subject. In particular embodiments, the invention provides a highly sensitive and precise quantitative method for diagnosis, post-operative surveillance, and monitoring evidence of disease over time in the adjuvant setting (i.e. treatment with BRAF-inhibitors).
Public/Granted literature
- US20170362661A1 METHODS FOR DETECTING BRAF IN CANCER Public/Granted day:2017-12-21
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