The application discloses a method and system for segmenting a lung image. The method may include obtaining a target image relating to a lung region. The target image may include a plurality of image slices. The method may also include segmenting the lung region from the target image, identifying an airway structure relating to the lung region, and identifying one or more fissures in the lung region. The method may further include determining one or more pulmonary lobes in the lung region.