Invention Grant
- Patent Title: Immunoglobulin formulation and method of preparation thereof
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Application No.: US15914980Application Date: 2018-03-07
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Publication No.: US10954303B2Publication Date: 2021-03-23
- Inventor: David J. Burke , Shaun E. Buckley , Sherwood Russ Lehrman , Barbara Horsey O'Connor , James Callaway , Christopher P. Phillips
- Applicant: BIOGEN MA INC.
- Applicant Address: US MA Cambridge
- Assignee: BIOGEN MA INC.
- Current Assignee: BIOGEN MA INC.
- Current Assignee Address: US MA Cambridge
- Agent Todd A. Lorenz
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A61K47/02 ; A61K47/26 ; A61K39/00

Abstract:
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
Public/Granted literature
- US20180194843A1 IMMUNOGLOBULIN FORMULATION AND METHOD OF PREPARATION THEREOF Public/Granted day:2018-07-12
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