Invention Grant
- Patent Title: Bubble-shaped adaptor element and method of constructing sequencing library with bubble-shaped adaptor element
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Application No.: US15528362Application Date: 2014-11-21
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Publication No.: US10954559B2Publication Date: 2021-03-23
- Inventor: Yuan Jiang , Xia Zhao , Qiaoling Li , Shengmao Liu , Bo Wang , Li Chen , Wenwei Zhang , Hui Jiang , Radoje Drmanac
- Applicant: MGI TECH CO., LTD.
- Applicant Address: CN Shenzhen
- Assignee: MGI TECH CO., LTD.
- Current Assignee: MGI TECH CO., LTD.
- Current Assignee Address: CN Shenzhen
- Agency: Westman, Champlin & Koehler, P.A.
- Agent Z. Peter Sawicki; Amanda M. Prose
- International Application: PCT/CN2014/091952 WO 20141121
- International Announcement: WO2016/078095 WO 20160526
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6869 ; C12Q1/6855 ; C12Q1/6874
Abstract:
Provided are an adaptor element in a bubble shape, a method of constructing a sequencing library with such an adapter element. The adaptor element is a hybrid formed with a long-chain nucleic acid A and a short-chain nucleic acid B. The hybrid is in the bubble shape with paired regions at two terminals and a non-paired region in the middle.
Public/Granted literature
Information query
