- Patent Title: Methods for treating lung inflammation with an anti-ASC antibody
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Application No.: US16847054Application Date: 2020-04-13
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Publication No.: US10961306B2Publication Date: 2021-03-30
- Inventor: Robert W. Keane , W. Dalton Dietrich , Juan Pablo De Rivero Vaccari , Helen M. Bramlett , Roberta Brambilla
- Applicant: University of Miami
- Applicant Address: US FL Miami
- Assignee: University of Miami
- Current Assignee: University of Miami
- Current Assignee Address: US FL Miami
- Agency: Cooley LLP
- Main IPC: C07K16/24
- IPC: C07K16/24 ; A61P11/00 ; A61P25/28 ; A61K39/00 ; A61P29/00 ; C07K16/18 ; A61P25/00 ; A61K31/727 ; A61K39/395 ; A61P25/14 ; A61P37/06
Abstract:
The compositions and methods described herein include agents that inhibit inflammasome signaling in the mammal such as antibodies directed against inflammasome components used alone or in combination with extracellular vesicle uptake inhibitor(s). Also described herein are compositions and methods of use thereof for treating multiple sclerosis.
Public/Granted literature
- US20200347124A1 METHODS AND COMPOSITIONS FOR TREATING LUNG INFLAMMATION Public/Granted day:2020-11-05
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