Invention Grant
- Patent Title: Methods for predicting graft alterations
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Application No.: US15537337Application Date: 2015-12-18
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Publication No.: US10961580B2Publication Date: 2021-03-30
- Inventor: Sophie Brouard , Magali Giral , Richard Danger
- Applicant: INSERM (Institut National de la Santé et de la Recherche Médicale) , Université de Nantes , Centre Hospitalier Universitaire de Nantes
- Applicant Address: FR Paris; FR Nantes; FR Nantes
- Assignee: INSERM (Institut National de la Santé et de la Recherche Médicale),Université de Nantes,Centre Hospitalier Universitaire de Nantes
- Current Assignee: INSERM (Institut National de la Santé et de la Recherche Médicale),Université de Nantes,Centre Hospitalier Universitaire de Nantes
- Current Assignee Address: FR Paris; FR Nantes; FR Nantes
- Agency: Klarquist Sparkman, LLP
- Priority: EP14307111 20141219
- International Application: PCT/EP2015/080423 WO 20151218
- International Announcement: WO2016/097259 WO 20160623
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C12Q1/6883 ; G01N33/50

Abstract:
The invention relates to a method for predicting graft alterations in a transplanted patient, comprising a step of determining the expression levels of bactericidal/permeability-increasing protein (BPI), chemokine (C motif) ligand 1 (XCL1) and thioredoxin domain containing 3 (TXNDC3) genes in a biological sample obtained from said transplanted patient.
Public/Granted literature
- US20170342494A1 METHODS FOR PREDICTING GRAFT ALTERATIONS Public/Granted day:2017-11-30
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