The embodiments of the present disclosure provide a display substrate and a display device, which relate to the field of display technologies, to solve the problem that a saw-toothed display effect occurs at an edge of an AA area when displaying if the edge of the AA area is non-linear. The display substrate includes a black matrix. The display substrate is provided with a display area, and at least a part of an edge of the display area has an irregular edge having a concave-convex shape. The display area has a plurality of subpixels arranged in a matrix form, and has a vision weakening area close to the irregular edge. In the vision weakening area, the black matrix includes a light shielding block located in the subpixel.