An electronic device with a detachable structure is provided. The electronic device includes a bracket, a connector, a module frame and a carried unit. The bracket includes a bracket wedging portion, wherein the bracket has a receiving recess, the receiving recess has a first side and a second side, the first side is opposite to the second side, and the bracket wedging portion is located on the first side. The connector is disposed on the second side of the bracket. The module frame is detachably connected to the bracket. The module frame can be easily attached to or detached from the bracket, reducing the time and effort required for assembly.