Invention Grant
- Patent Title: Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors
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Application No.: US15794231Application Date: 2017-10-26
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Publication No.: US10968264B2Publication Date: 2021-04-06
- Inventor: Mark Macielag , Raymond J Patch , Rui Zhang , Martin A Case , Yue-Mei Zhang , Mark Wall
- Applicant: JANSSEN PHARMACEUTICA NV
- Applicant Address: DE Beerse
- Assignee: JANSSEN PHARMACEUTICA NV
- Current Assignee: JANSSEN PHARMACEUTICA NV
- Current Assignee Address: DE Beerse
- Agency: Ice Miller LLP
- Main IPC: C07K14/575
- IPC: C07K14/575 ; A61K47/68 ; C07K16/24 ; A61K9/00 ; A61K38/17 ; A61K38/26 ; C07K1/06 ; C07K1/107 ; A61K47/64 ; A61P3/10 ; A61K49/00 ; C07K1/12 ; C07K1/18 ; C07K5/02 ; A61K47/60 ; A61P3/08 ; A61P3/00 ; A61P3/04 ; A61P3/06 ; A61K38/22 ; A61K45/06 ; C07K16/00 ; A61K38/00 ; A61K39/00
Abstract:
The present invention comprises compounds of Formula I. wherein: Z4, Z7, Z9, Z11, Z22, Z23, Z26, Z30, Z34, Z35, p, m, n, q, and BRIDGE are defined in the specification. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel compounds are useful for preventing, treating or ameliorating diseases and disorders, such as obesity, type 2 diabetes, the metabolic syndrome, insulin resistance, and dyslipidemia, among others.
Public/Granted literature
- US20180127476A1 CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS Public/Granted day:2018-05-10
Information query
