Invention Grant
- Patent Title: Polymerase variants and uses thereof
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Application No.: US16694985Application Date: 2019-11-25
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Publication No.: US10968438B2Publication Date: 2021-04-06
- Inventor: Aruna Ayer , Cleoma Arnold , Charles Wayan Schwab , Eileen Thai , Ilya Lederman , Colin Alexander McGaw , Tyler O'Brien Shultz
- Applicant: Roche Sequencing Solutions, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee Address: US CA Pleasanton
- Agency: Roche Sequencing Solutions, Inc.
- Main IPC: C12N9/12
- IPC: C12N9/12
Abstract:
Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227, I295, Y342, T343, I357, S360, L361, I363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, Q546, A547, L549, I550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624, I628, Y629, R632, N635, M641, A643, I644, T647, I648, T651, I652, K655, W656, D657, V658, H660, F662, L690 and combinations thereof.
Public/Granted literature
- US20200087636A1 POLYMERASE VARIANTS AND USES THEREOF Public/Granted day:2020-03-19
Information query
