A pixel driving circuit comprises a pixel array, data lines and scan lines. The pixel array includes a plurality of pixel units having four sub-pixels with different colors. All of the sub-pixels are arranged in a dot inversion arrangement, and positive and negative polarities of the sub-pixels are alternately arranged. The data lines and the scan lines are orthogonally disposed to define a pixel array. Two of the scan lines are provided for each column of pixel units, and two of the data lines are provided for each row of pixel units. Each data line is connected to two closest sub-pixels with the same polarity when passing through one column of pixel units, and all the sub-pixels connected to the same data line in the row direction have the same polarity. The sub-pixels connected to the adjacent data lines have reverse polarities.