Methods and systems are disclosed for providing physical layer resources to a plurality of medium access control (MAC) instances that are associated with different serving sites that are independently scheduled. For example, a WTRU may utilize a first physical layer configuration for transmitting to a first serving site associated with a first MAC instance. The WTRU may utilize a second physical layer configuration for transmitting to a second serving site associated with a second MAC instance. The WTRU may prevent conflicts between transmission requests from the first MAC instance and transmission requests from the second MAC instance. For example, preventing the conflicts may include utilizing one or more of time segregation or frequency segregation for transmissions associated with the first MAC instance and transmissions associated with the second MAC instance.