Invention Grant
- Patent Title: Factor H-Fc immunotheraphy
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Application No.: US15770965Application Date: 2016-10-27
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Publication No.: US10975131B2Publication Date: 2021-04-13
- Inventor: Sanjay Ram , Douglas T. Golenbock , Alberto Visintin , Jutamas Shaughnessy
- Applicant: University of Massachusetts
- Applicant Address: US MA Boston
- Assignee: University of Massachusetts
- Current Assignee: University of Massachusetts
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2016/059072 WO 20161027
- International Announcement: WO2017/075189 WO 20170504
- Main IPC: C07K14/47
- IPC: C07K14/47 ; A61P31/04 ; A61K38/00
Abstract:
Fusion proteins comprising human FH domains 18-20 (FH18-20) linked via an optional linker to IgG Fc, wherein the FH has mutation of D to G at position 1119 in domain 19; FHD1119G/Fc), and methods of use thereof, e.g., to treat pathogen infections.
Public/Granted literature
- US20180305425A1 Factor H-Fc Immunotheraphy Public/Granted day:2018-10-25
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