Invention Grant
- Patent Title: Controlled induction of human pancreatic progenitors produces functional beta-like cells
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Application No.: US15568736Application Date: 2016-04-22
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Publication No.: US10975355B2Publication Date: 2021-04-13
- Inventor: Matthias Hebrok , Holger Andreas Russ
- Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Oakland
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2016/028963 WO 20160422
- International Announcement: WO2016/172564 WO 20161027
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C07K14/62 ; C07K14/50 ; C07K14/485 ; C07K14/495 ; A61P3/10 ; A61K35/39
Abstract:
Methods are provided for the simple, fast, effective and safe directed differentiation of embryonic stem cells into pancreatic beta-like cells secreting insulin in response to glucose levels. The cells are useful transplant therapeutics for diabetic individuals.
Public/Granted literature
- US20180087034A1 Controlled Induction of Human Pancreatic Progenitors Produces Functional Beta-Like Cells Public/Granted day:2018-03-29
Information query
