Invention Grant
- Patent Title: Retargeting of viruses or VLPs
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Application No.: US16482771Application Date: 2018-02-01
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Publication No.: US10975359B2Publication Date: 2021-04-13
- Inventor: Jens Gruber , Stefan Schneider , Ellen Eckermann-Felkl , Alina Mosblech , Arnd Steuernagel , Dennis Wegener , Julian Plaga
- Applicant: Deutsches Primatenzentrum GmbH Leibniz-Institut für Primatenforschung
- Applicant Address: DE Göttingen
- Assignee: Deutsches Primatenzentrum GmbH Leibniz-Institut für Primatenforschung
- Current Assignee: Deutsches Primatenzentrum GmbH Leibniz-Institut für Primatenforschung
- Current Assignee Address: DE Göttingen
- Agency: Foley Hoag LLP
- Priority: EP17154380 20170202
- International Application: PCT/EP2018/052523 WO 20180201
- International Announcement: WO2018/141849 WO 20180809
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K47/68 ; A61K47/69 ; C07K16/32

Abstract:
The present invention relates to a method of producing a polyomavirus or polyomavirus-derived virus-like particle (vlp) carrying on its surface at least one targeting molecule that binds to a cell of interest. Furthermore, the present invention relates to a composition comprising such a polyomavirus or polyomavirus-derived vlp and to the use of the polyomavirus or polyomavirus-derived vlp of the invention or the composition of the invention for use as a medicament. The present invention further relates to a kit comprising the polyomavirus or polyomavirus-derived vlp or the composition of the invention.
Public/Granted literature
- US20190352617A1 RETARGETING OF VIRUSES OR VLPs Public/Granted day:2019-11-21
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