Invention Grant
- Patent Title: Method for do novo biosynthesis of chondroitin sulfate
-
Application No.: US15808944Application Date: 2017-11-10
-
Publication No.: US10975405B2Publication Date: 2021-04-13
- Inventor: Zhen Kang , Jian Chen , Guocheng Du , Zhengxiong Zhou
- Applicant: Jiangnan University
- Applicant Address: CN Wuxi
- Assignee: Jiangnan University
- Current Assignee: Jiangnan University
- Current Assignee Address: CN Wuxi
- Agency: IPro, PLLC
- Priority: CN201610997085.4 20161114,CN201611149169.9 20161214
- Main IPC: C12N11/08
- IPC: C12N11/08 ; C12P19/26 ; C12N9/10
Abstract:
The present invention relates to a method for chondroitin sulfate biosynthesis, belongs to the field of pharmaceuticals. CS was biosynthesized by sulfating the chondroitin with C4ST or C6ST in Tris-HCl buffer assisted with 3′-phosphoadenosine 5′-phophosulfate (PAPS). C4ST and C46ST came from bioengineered Escherichia coli or Pichia pastoris. Chondroitin came from bioengineered Bacillus subtilis 168.
Public/Granted literature
- US20180135089A1 Method for Do Novo Biosynthesis of Chondroitin Sulfate Public/Granted day:2018-05-17
Information query
