Invention Grant
- Patent Title: Systematic discovery, maturation and extension of peptide binders to proteins
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Application No.: US16191407Application Date: 2018-11-14
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Publication No.: US10976317B2Publication Date: 2021-04-13
- Inventor: Jigar Patel , Victor Lyamichev , Thomas Albert
- Applicant: Roche Sequencing Solutions, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee Address: US CA Pleasanton
- Agency: Foley & Lardner LLP
- Main IPC: C40B30/04
- IPC: C40B30/04 ; G01N33/573 ; C07K1/04 ; G01N33/574 ; G01N33/68 ; C07K7/06
Abstract:
The invention comprises systems, methods and arrays for identification and optimization of novel peptide binders to protein targets. Embodiments include steps of peptide binder discovery, core peptide maturation, N-terminal and C-terminal extension and kinetics analysis of the final peptide binder.
Public/Granted literature
- US20190086411A1 SYSTEMATIC DISCOVERY, MATURATION AND EXTENSION OF PEPTIDE BINDERS TO PROTEINS Public/Granted day:2019-03-21
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