An actuation system used to actuate one or more buttons on a remote control device, such as a key fob, based upon commands that are generated from a mobile device. The actuation system includes a key fob enclosure located remotely from the vehicle. When a command is received on the mobile device, the command is relayed to a controller within the key fob enclosure, causing a button on the key fob to be depressed. The RF signal from the key fob is translated into a digital message which is relayed to a proxy remote located within the vehicle. The proxy remote, in turn, translates the digital message to an RF signal which is transmitted and received by systems within the vehicle. In this manner, the proxy remote is able to communicate using RF signals with the vehicle without requiring the key fob to be located near the vehicle.