Embodiments of the present disclosure provide a current amplification circuitry and a driving method thereof, and a fingerprint detection device. The current amplification circuitry includes a voltage control circuit, a plurality of first current amplification circuits, and a second current amplification circuit. The voltage control circuit provides a voltage control signal to the plurality of first current amplification circuits. The first current amplification circuit includes a current mirror, and the current mirror is coupled to a voltage input terminal, the voltage control circuit, and a first input terminal of the second current amplification circuit. The first current amplification circuit amplifies a current from the voltage input terminal according to the voltage control signal provided by the voltage control circuit, and provides the amplified current to the second current amplification circuit. The second current amplification circuit is coupled to the voltage input terminal via a second input terminal and amplifies the amplified current.