Cleaning devices disclosed herein provide, for example, an effective and reliable approach for cleaning an exposed surface of an imaging element (e.g., a lens) of an imaging device (e.g., an endoscope). Cleaning devices disclosed herein enable an imaging element to be cleaned while located within a concealed operation site (e.g., an in-vivo surgical site). To enhance imaging device compatibility, cleaning devices disclosed herein have integral therewith a seating adjustor that allows a user to selectively adjust the position of an imaging device seated thereon. Cleaning devices disclosed herein are thus able to accommodate imaging devices that would otherwise be incompatible due to a distance between the imaging element of the imaging device and a position of a cleaning member of the cleaning device being either too big or too small.