Systems, methods and apparatus of drowsiness detection for vehicle control. For example, a vehicle includes: a camera configured to face a driver of the vehicle and generate a sequence of images of the driver driving the vehicle; an artificial neural network configured to analyze the sequence of images and classify, based on the sequence of images, whether the driver is in a drowsy state; and an infotainment system configured to provide instructions to the driver in response to a classification by the artificial neural network that the driver is in the drowsy state.