Invention Grant
- Patent Title: Therapeutic agent for ischemic diseases
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Application No.: US15544565Application Date: 2016-01-18
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Publication No.: US10993972B2Publication Date: 2021-05-04
- Inventor: Yuko Wada , Yuko Shimatani , Takashi Yano , Takeshi Masaki
- Applicant: Shinshu University , Anaeropharma Science, Inc.
- Applicant Address: JP Matsumoto; JP Tokyo
- Assignee: Shinshu University,Anaeropharma Science, Inc.
- Current Assignee: Shinshu University,Anaeropharma Science, Inc.
- Current Assignee Address: JP Matsumoto; JP Tokyo
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: JPJP2015-007760 20150119
- International Application: PCT/JP2016/051293 WO 20160118
- International Announcement: WO2016/117508 WO 20160728
- Main IPC: A61K35/745
- IPC: A61K35/745 ; A61K47/26 ; A61K48/00 ; C12Q1/02 ; A61K35/74 ; C12N15/09 ; C12N15/74
Abstract:
Provided are: a transformation plasmid for transforming anaerobes and enabling highly efficient and stable secretory expression of a target protein; a gene delivery carrier formed from said anaerobes transformed by said plasmid; a pharmaceutical composition including said gene delivery carrier; and a method for diagnosing or treating an ischemic disease utilizing these. Also provided are: a novel secretory signal; a transformation plasmid including said secretory signal; a gene delivery carrier formed from anaerobes transformed by said plasmid; a pharmaceutical composition including said gene delivery carrier; and a method for diagnosing or treating an ischemic disease utilizing these.
Public/Granted literature
- US20180360893A1 THERAPEUTIC AGENT FOR ISCHEMIC DISEASES Public/Granted day:2018-12-20
Information query
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