Invention Grant
- Patent Title: Nucleic acid-polypeptide compositions and methods of inducing exon skipping
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Application No.: US16128450Application Date: 2018-09-11
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Publication No.: US10994020B2Publication Date: 2021-05-04
- Inventor: Arthur A. Levin , Andrew John Geall , Venkata Ramana Doppalapudi , Michael Caramian Cochran , Hanhua Huang , Rob Burke
- Applicant: AVIDITY BIOSCIENCES, INC.
- Applicant Address: US CA La Jolla
- Assignee: AVIDITY BIOSCIENCES, INC.
- Current Assignee: AVIDITY BIOSCIENCES, INC.
- Current Assignee Address: US CA La Jolla
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K47/68 ; C12N15/113 ; C07K16/28 ; C07K14/00 ; A61K47/64 ; A61K47/60 ; A61P21/00 ; A61K31/713 ; A61K31/7088 ; A61K48/00 ; C07K16/40 ; A61K38/00
Abstract:
Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
Public/Granted literature
- US20180369400A1 NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING Public/Granted day:2018-12-27
Information query
