Invention Grant
- Patent Title: Argonaute protein-double stranded RNA complexes and uses related thereto
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Application No.: US15977778Application Date: 2018-05-11
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Publication No.: US10994025B2Publication Date: 2021-05-04
- Inventor: Jiahe Li , Paula T. Hammond , Yanpu He , Wade Wang
- Applicant: Massachusetts Institute of Technology
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Agency: Foley Hoag LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/113 ; A61K9/00 ; A61K38/17 ; A61K47/42 ; C12N15/11
Abstract:
The invention relates to methods of improving efficacy and enhancing silencing of target genes using Ago2 protein-dsRNA complex (RNP) of the invention.
Public/Granted literature
- US20180326092A1 ARGONAUTE PROTEIN-DOUBLE STRANDED RNA COMPLEXES AND USES RELATED THERETO Public/Granted day:2018-11-15
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