Invention Grant
- Patent Title: Scalable manufacturing process to produce recombinant lentiviral vectors in serum-free suspension cell culture system
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Application No.: US15699613Application Date: 2017-09-08
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Publication No.: US10994028B2Publication Date: 2021-05-04
- Inventor: Guang Qu , John Fraser Wright
- Applicant: The Children's Hospital of Philadelphia
- Applicant Address: US PA Philadelphia
- Assignee: The Children's Hospital of Philadelphia
- Current Assignee: The Children's Hospital of Philadelphia
- Current Assignee Address: US PA Philadelphia
- Agency: Pillsbury Winthrop Shaw Pittman LLP
- Agent Robert M. Bedgood
- Main IPC: C12N7/02
- IPC: C12N7/02 ; C12N7/00 ; C12N15/867 ; A61K48/00
Abstract:
Methods for preparing highly purified rLV vector formulations at the scale needed to meet anticipated demand for human gene therapy are provided.
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