Invention Grant
- Patent Title: Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis B
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Application No.: US15681309Application Date: 2017-08-18
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Publication No.: US10995064B2Publication Date: 2021-05-04
- Inventor: Koen Vandyck , Stefaan Julien Last , Geert Rombouts , Wim Gaston Verschueren , Pierre Jean-Marie Bernard Raboisson
- Applicant: JANSSEN SCIENCES IRELAND UC
- Applicant Address: IE Little Island
- Assignee: JANSSEN SCIENCES IRELAND UC
- Current Assignee: JANSSEN SCIENCES IRELAND UC
- Current Assignee Address: IE Little Island
- Priority: EP12185055 20120919,EP12190837 20121031,EP13157230 20130228,EP13169574 20130528,EP12182076 20130823
- Main IPC: A61K31/4164
- IPC: A61K31/4164 ; A61K31/426 ; C07D207/36 ; C07D277/36 ; C07C311/37 ; C07C311/14 ; A61K31/18 ; A61K31/337 ; A61K31/341 ; A61K31/351 ; A61K31/44 ; A61K31/4453 ; A61K31/4468 ; C07C311/16 ; C07C311/20 ; C07C311/51 ; C07D211/96 ; C07D305/08 ; C07D307/22 ; C07D205/04 ; C07D207/273 ; C07D213/42 ; C07D307/60 ; C07D213/81 ; C07D213/82 ; C07D333/38 ; C07D333/48 ; C07D233/90 ; C07D491/107 ; C07D207/14 ; C07D493/08 ; C07D277/56 ; C07D211/28 ; C07D295/13 ; C07D211/56 ; C07D211/76 ; C07D295/26 ; C07D307/68 ; A61K31/34 ; A61K31/397 ; A61K31/495 ; A61K31/5375 ; A61K31/55 ; C07D223/06 ; C07D233/84 ; C07D309/14 ; A61K31/401 ; A61K45/06
Abstract:
Inhibitors of HBV replication of Formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein B, R1, R2 and R4 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
Public/Granted literature
- US20180127361A1 SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B Public/Granted day:2018-05-10
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