Invention Grant
- Patent Title: Zaindole derivatives and their use as ERK kinase inhibitors
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Application No.: US15777386Application Date: 2016-11-17
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Publication No.: US10995089B2Publication Date: 2021-05-04
- Inventor: Jean-François Guichou , Cédric Bories , Clément Geoffroy , Charline Duquenne , Muriel Gelin , Gilles Labesse , Yannick Bessin , Loic Mathieu
- Applicant: AGV Discovery ENSCM , Institut National de la Sante et de la Recherche Medicale (INSERM) , Centre National de la Recherche Scientifique (CNRS) , Universite de Montpellier
- Applicant Address: FR Montpellier; FR Paris; FR Paris; FR Montpellier
- Assignee: AGV Discovery ENSCM,Institut National de la Sante et de la Recherche Medicale (INSERM),Centre National de la Recherche Scientifique (CNRS),Universite de Montpellier
- Current Assignee: AGV Discovery ENSCM,Institut National de la Sante et de la Recherche Medicale (INSERM),Centre National de la Recherche Scientifique (CNRS),Universite de Montpellier
- Current Assignee Address: FR Montpellier; FR Paris; FR Paris; FR Montpellier
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: EP15306835 20151118
- International Application: PCT/EP2016/078080 WO 20161117
- International Announcement: WO2017/085230 WO 20170526
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P35/00 ; C07D519/00 ; C07F9/6561 ; C07D491/048 ; C07D491/107 ; C07D491/113

Abstract:
The present invention concerns a compound of formula (I): H or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity in particular ERK2 activity, it also concerns prodrugs of these compounds.
Public/Granted literature
- US20200283432A1 ZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS Public/Granted day:2020-09-10
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