Invention Grant
- Patent Title: Peptide exhibiting hydrolytic activity and use thereof
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Application No.: US16067764Application Date: 2017-01-06
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Publication No.: US10995119B2Publication Date: 2021-05-04
- Inventor: Toshifumi Akizawa , Tadashi Yamamoto
- Applicant: Okinawa Institute of Science and Technology School Corporation
- Applicant Address: JP Okinawa
- Assignee: Okinawa Institute of Science and Technology School Corporation
- Current Assignee: Okinawa Institute of Science and Technology School Corporation
- Current Assignee Address: JP Okinawa
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: JP2016-068496 20160330
- International Application: PCT/JP2017/000341 WO 20170106
- International Announcement: WO2017/119511 WO 20170713
- Main IPC: C07K7/08
- IPC: C07K7/08 ; C07K14/47 ; C12N9/50

Abstract:
The present invention provides a novel molecule that catalyzes a hydrolysis reaction and is different from enzyme proteins. The catalytic peptide according to the present invention is a catalytic peptide that catalyzes a hydrolysis reaction, including at least one peptide selected from the group consisting of the following peptides (A1) to (A4): (A1) a peptide consisting of Box A and at least one of an upstream region and a downstream region therefrom in a Tob/BTG protein; (A2) a peptide consisting of a partial region of the peptide (A1); (A3) a peptide that consists of an amino acid sequence obtained by deletion, substitution, addition, and/or insertion of one or more amino acids in an amino acid sequence of the peptide (A1) or (A2) and has hydrolysis activity; and (A4) a peptide consisting of an amino acid sequence with a sequence identity of at least 85% to the amino acid sequence of the peptide (A1) or (A2) and having hydrolysis activity.
Public/Granted literature
- US20190023741A1 NOVEL PEPTIDE EXHIBITING HYDROLYTIC ACTIVITY AND USE THEREOF Public/Granted day:2019-01-24
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