Invention Grant
- Patent Title: Methods for inhibiting atherosclerosis by administering an anti-PCSK9 antibody
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Application No.: US16505074Application Date: 2019-07-08
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Publication No.: US10995150B2Publication Date: 2021-05-04
- Inventor: William J. Sasiela , Viktoria Gusarova , Anusch Peyman , Hans Ludwig Schäfer , Uwe Schwahn
- Applicant: REGENERON PHARMACEUTICALS, INC. , SANOFI BIOTECHNOLOGY
- Applicant Address: US NY Tarrytown; FR Paris
- Assignee: REGENERON PHARMACEUTICALS, INC.,SANOFI BIOTECHNOLOGY
- Current Assignee: REGENERON PHARMACEUTICALS, INC.,SANOFI BIOTECHNOLOGY
- Current Assignee Address: US NY Tarrytown; FR Paris
- Agency: Lathrop Gpm LLP
- Agent James H. Velema, Esq.; James V. DeGiulio, Esq.
- Priority: EP13305762 20130607,EP13306436 20131018
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K9/10 ; C07K16/40 ; A61P9/10 ; A61K31/4015 ; C07K14/47 ; A61K39/00
Abstract:
The present invention provides methods and compositions for inhibiting atherosclerotic plaque formation in a subject. In certain embodiments, the methods of the present invention comprise selecting a subject who has, or is at risk of developing, atherosclerosis, and administering to the subject a pharmaceutical composition comprising a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody, or antigen binding protein.
Public/Granted literature
- US20200071422A1 METHODS FOR INHIBITING ATHEROSCLEROSIS BY ADMINISTERING AN INHIBITOR OF PCSK9 Public/Granted day:2020-03-05
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