Invention Grant
- Patent Title: Transaminase polypeptides
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Application No.: US16717596Application Date: 2019-12-17
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Publication No.: US10995323B2Publication Date: 2021-05-04
- Inventor: Ish K. Dhawan , Gregory Miller , Xiyun Zhang
- Applicant: Codexis Inc.
- Applicant Address: US CA Redwood City
- Assignee: Codexis Inc.
- Current Assignee: Codexis Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- Main IPC: C12N9/10
- IPC: C12N9/10 ; C12P13/00 ; C12P41/00

Abstract:
The present disclosure provides engineered transaminase enzymes having improved properties as compared to a naturally occurring wild-type transaminase enzyme. Also provided are polynucleotides encoding the engineered transaminase enzymes, host cells capable of expressing the engineered transaminase enzymes, and methods of using the engineered transaminase enzymes to synthesize a variety of chiral compounds.
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