Invention Grant
- Patent Title: SYNP159, a promoter for the specific expression of genes in rod photoreceptors
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Application No.: US15780557Application Date: 2016-12-01
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Publication No.: US10995344B2Publication Date: 2021-05-04
- Inventor: Dominik Hartl , Josephine Juettner , Arnaud Krebs , Botond Roska , Dirk Schuebeler
- Applicant: Friedrich Miescher Institute for Biomedical Research
- Applicant Address: CH Basel
- Assignee: Friedrich Miescher Institute for Biomedical Research
- Current Assignee: Friedrich Miescher Institute for Biomedical Research
- Current Assignee Address: CH Basel
- Agent Joshua J. Buchman
- Priority: EP15197899 20151203
- International Application: PCT/IB2016/057263 WO 20161201
- International Announcement: WO2017/093931 WO 20170608
- Main IPC: C12N15/79
- IPC: C12N15/79 ; A61K48/00 ; C12N15/86 ; C07K14/195 ; C07K14/405

Abstract:
The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 400 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod photoreceptors of a gene when operatively linked to a nucleic acid sequence coding for said gene.
Public/Granted literature
- US20180355377A1 SYNP159, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS Public/Granted day:2018-12-13
Information query
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