Invention Grant
- Patent Title: Engineered proline hydroxylase polypeptides and methods
-
Application No.: US16913761Application Date: 2020-06-26
-
Publication No.: US10995349B2Publication Date: 2021-05-04
- Inventor: Haibin Chen , Yong Koy Bong , Fabien L. Cabirol , Anupam Gohel Prafulchandra , Tao Li , Jeffrey C. Moore , Martina Quintanar-Audelo , Yang Hong , Steven J. Collier , Derek Smith
- Applicant: Codexis, Inc.
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- Main IPC: C12N11/10
- IPC: C12N11/10 ; C12P17/12 ; C12P17/18 ; C12N9/02 ; C12P13/24 ; C12P13/04
Abstract:
The present disclosure provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.
Public/Granted literature
- US20200325510A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS Public/Granted day:2020-10-15
Information query
