Invention Grant
- Patent Title: Compositions and methods for improving sample identification in indexed nucleic acid libraries
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Application No.: US15959897Application Date: 2018-04-23
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Publication No.: US10995369B2Publication Date: 2021-05-04
- Inventor: Eric Hans Vermaas , Mahdieh Khosroheidari , Angela Kalbande
- Applicant: Illumina, Inc.
- Applicant Address: US CA San Diego
- Assignee: Illumina, Inc.
- Current Assignee: Illumina, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Mueting Raasch Group
- Main IPC: C12Q1/6855
- IPC: C12Q1/6855 ; C12Q1/6806 ; C40B50/06
Abstract:
The present invention is concerned with compositions and methods for improving the rate of correct sample identification in indexed nucleic acid library preparations for multiplex next generation sequencing by exonuclease treatment after protective adapters are ligated to target polynucleotides to degrade unincorporated adapters prior to amplification and sequencing.
Public/Granted literature
- US20180305751A1 COMPOSITIONS AND METHODS FOR IMPROVING SAMPLE IDENTIFICATION IN INDEXED NUCLEIC ACID LIBRARIES Public/Granted day:2018-10-25
Information query
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