Containment vessels are adapted to facilitate blast and dispersion mitigation. According to one example, a containment vessel may include at least one containment layer. At least one expansion member may be coupled to the at least one containment layer to apply a force sufficient to expand a perimeter of the containment layer(s) laterally outward. A closure system may be coupled with the containment layer(s), where the closure system is configured to cinch the perimeter of the containment layer(s) around a target object without manual intervention. Unmanned aerial vehicle (UAV) including a containment vessel, as well as methods of making a containment vessel are also disclosed. Other aspects, embodiments, and features are also included.