Invention Grant
- Patent Title: Biomarkers for assessment of preeclampsia
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Application No.: US15833656Application Date: 2017-12-06
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Publication No.: US10996228B2Publication Date: 2021-05-04
- Inventor: Srinivasa R. Nagalla , Eric S. Bean
- Applicant: DiabetOmics, LLC
- Applicant Address: US OR Hillsboro
- Assignee: DiabetOmics, LLC
- Current Assignee: DiabetOmics, LLC
- Current Assignee Address: US OR Hillsboro
- Agency: Schwabe Williamson & Wyatt, PC
- Main IPC: G01N33/68
- IPC: G01N33/68

Abstract:
Disclosed herein are screening tools for fetal/maternal wellness, such as biomarkers for assessing preeclampsia. More specifically, methods are disclosed for assessing the risk of preeclampsia in a subject, the methods including obtaining a first serum sample from the subject, determining a level of glycosylated fibronectin (GlyFn) in the first serum sample, and comparing the determined level of GlyFn with a control value, wherein an elevation in the determined level of GlyFn in the first serum sample relative to the control value indicates that the subject is at increased risk of preeclampsia. Also disclosed are methods of determining the risk of preeclampsia in a subject during a first, second, or third trimester, methods of assessing severity and progression of preeclampsia and complications of a risk of low birth weight or HELLP syndrome.
Public/Granted literature
- US20180095090A1 BIOMARKERS FOR ASSESSMENT OF PREECLAMPSIA Public/Granted day:2018-04-05
Information query
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