Invention Grant
- Patent Title: Virus-PCION complex having enhanced antitumor effect by using electromagnetic field
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Application No.: US16432825Application Date: 2019-06-05
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Publication No.: US11000590B2Publication Date: 2021-05-11
- Inventor: Chae Ok Yun , Joung-Woo Choi
- Applicant: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
- Applicant Address: KR Seoul
- Assignee: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
- Current Assignee: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
- Current Assignee Address: KR Seoul
- Agency: Adsero IP
- Priority: KR10-2016-0030514 20160314
- Main IPC: A61K41/00
- IPC: A61K41/00 ; C12N7/00 ; C12N15/86 ; A61K9/51 ; A61K47/60 ; A61K47/64 ; A61K47/69 ; A61K35/761
Abstract:
The present disclosure relates to a composition for transduction of a virus in a cell by using a crosslinked product of PEGylated magnetic nanoparticles and catechol grafted poly-L-lysine by application of an external magnetic field. When the composition is used, a virus may be delivered into cells more rapidly and efficiently than in intracellular uptake of a virus by CAR-mediated endocytosis.
Public/Granted literature
- US20190298831A1 VIRUS-PCION COMPLEX HAVING ENHANCED ANTITUMOR EFFECT BY USING ELECTROMAGNETIC FIELD Public/Granted day:2019-10-03
Information query
